The possible role of machine learning in detection of increased cardiovascular risk patients - KSC MR Study (design).

Introduction: Currently, just a few major parameters are used for cardiovascular (CV) risk quantification to identify many of the high-risk subjects; however, they leave a lot of them with an underestimated level of CV risk which does not reflect the reality. Material and methods: The submitted study design of the Kosice Selective Coronarography Multiple Risk (KSC MR) Study will use computer analysis of coronary angiography results of admitted patients along with broad patients' characteristics based on questionnaires, physical findings, laboratory and many other examinations. Results: Obtained data will undergo machine learning protocols with the aim of developing algorithms which will include all available parameters and accurately calculate the probability of coronary artery disease. Conclusions: The KSC MR study results, if positive, could establisha base for development of proper software for revealing high-risk patients, as well as patients with suggested positive coronary angiography findings, based on the principles of personalised medicine.

Recent Advances in ASIC Development for Enhanced Performance M-Sequence UWB Systems.

Short-range ultra-wideband (UWB) radar sensors belong to very promising sensing techniques that have received vast attention recently. The M-sequence UWB sensing techniques for radio detection and ranging feature several advantages over the other short-range radars, inter alia superior integration capabilities. The prerequisite to investigate their capabilities in real scenarios is the existence of physically available hardware, i.e., particular functional system blocks. In this paper, we present three novel blocks of M-sequence UWB radars exploiting application-specific integrated circuit (ASIC) technology. These are the integrated 15th-order M-sequence radar transceiver on one chip, experimental active Electronic Communication Committee (ECC) bandpass filter, and miniature transmitting UWB antenna with an integrated amplifier. All these are custom designs intended for the enhancement of capabilities of an M-sequence-based system family for new UWB short-range sensing applications. The design approaches and verification of the manufactured prototypes by measurements of the realized circuits are presented in this paper. The fine balance on technology capabilities (Fc of roughly 120 GHz) and thoughtful design process of the proposed blocks is the first step toward remarkably minimized devices, e.g., as System on Chip designs, which apparently allow broadening the range of new applications.